Correlation of rheoencephalography and laser Doppler flow: a rat study

Measuring brain electrical impedance (rheoencephalography) is a potential technique for noninvasive, continuous neuro-monitoring of cerebral blood flow autoregulation in humans. In the present rat study, we compared changes in cerebral blood flow autoregulation during CO2 inhalation measured by rheoencephalography to changes measured by laser Doppler flowmetry, an invasive continuous monitoring modality. Our hypothesis was that both modalities would reflect cerebral blood flow autoregulation.