ChemInform Abstract: An Asymmetric Organocatalytic Quadruple Domino Reaction Employing a Vinylogous Friedel-Crafts/Michael/Michael/Aldol Condensation Sequence.

Arne R. Philipps,Lars Fritze,Nico Erdmann,Dieter Enders

ChemInform（2015）

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摘要

Abstract Highly functionalized cyclohexenecarbaldehydes bearing a 1,1‐bis[4‐(dialkylamino)phenyl]ethene moiety and three contiguous stereogenic centers are synthesized with very good diastereoselectivity, virtually complete enantiomeric excess, and good functional group tolerance.

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friedel-crafts/michael/michael/aldol condensation sequence,cheminform abstract,reaction

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