S1948 Hypoxia-Inducible Factor (HIF)-1α Expression is Correlated With Transketolase Like (TKTl) 1 in Human Colorectal Cancer Cell Line SW480

Susanne Bentz, Esther Endlicher, Amjad Naami,Theresa Pesch,Silvia Kellermeier,Florian Obermeier, Peter Schubert,Achim Weber,Michael Fried,Stefan Gölder,Johannes F. Coy, Ruth Knüchel,Martin Hausmann, Gerhard Rogler

Gastroenterology(2010)

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摘要
under investigation, and further indicates the importance of dysplasia in the transition from inflammation to cancer in the colon.However, the up-regulation of Cox-2 in patients with CRC when compared to those with chronic inflammation seems to appear alongside carcinogenesis.It is probable that levels of certain proteins over-expressed in cancer increase during dysplasia while those of other proteins only become elevated after reaching said condition.
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关键词
human colorectal cancer,colorectal cancer,transketolase,hypoxia-inducible
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