Clostridioides difficile infection following dental antibiotic prescriptions in a cohort of US veterans.

Among 108 (0.05% of cohort) US veterans with a infection (CDI) within 30 days of a dental antibiotic prescription, 80% of patients received guideline-discordant antibiotics. Half had chronic gastrointestinal illness potentially exacerbating their CDI risk. More efforts are needed to improve antibiotic stewardship.