Cognitive function in early-phase schizophrenia-spectrum disorder: IQ subtypes, brain volume and immune markers.

Andrew J Watson,Annalisa Giordano,John Suckling,Thomas R E Barnes,Nusrat Husain,Peter B Jones,Carl R Krynicki,Stephen M Lawrie,Shôn Lewis,Naghmeh Nikkheslat,Carmine M Pariante,Rachel Upthegrove,Bill Deakin,Paola Dazzan,Eileen M Joyce

Psychological medicine（2022）

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摘要

The findings add validity of a neurodevelopmental subtype of schizophrenia identified by comparing estimated premorbid and current IQ and characterised by smaller premorbid brain volume and higher measures of low-grade inflammation (CRP).

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关键词

Cognition,inflammation,neuroimaging,psychosis,schizophrenia-spectrum disorder,subtypes

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