Analysis of rainbow trout TCRαβ/CD3 complex: An in-silico modeling approach

C Flores-Kossack, C Muñoz,N Fuentes,K Maisey

Molecular Immunology（2022）

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摘要

In mammals, the T lymphocyte receptor (TCR) is a multiprotein complex formed by the proteins TCRα, TCRβ, CD3ε, CD3γ, CD3δ, and CD3ζ. It is responsible for recognizing antigens processed and presented by antigen-presenting cells (APC). The TCR is located at the cytoplasmic membrane of the T lymphocyte but is functional assembled in the rough endoplasmic reticulum (RER).

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关键词

Trout,Lymphocytes,TCR,CD3,In-silico modeling

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