Quantitative Determination of Unbound Piperacillin and Imipenem in Biological Material from Critically Ill Using Thin-Film Microextraction-Liquid Chromatography-Mass Spectrometry
Molecules（2022）
关键词
beta-Lactam antibiotics,imipenem,piperacillin,ventilation-associated pneumonia (VAP),therapeutic drug monitoring (TDM),personalized therapy,solid-phase microextraction (SPME),thin-film microextraction (TFME),liquid chromatography-mass spectrometry (LC-MS),method validation
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