Association of IL-22 and IL-22RA1 gene variants in Iranian patients with colorectal cancer.

Seyed Reza Mohebbi,Khatoon Karimi,Fatemeh Rostami,Shabnam Kazemian,Pedram Azimzadeh,Hanieh Mirtalebi,Ehsan Nazemalhosseini-Mojarad,Hamid Asadzadeh Aghdaei,Reza Vafaee, Mohammad Hossain Heydari

Gastroenterology and hepatology from bed to bench（2021）

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摘要

The current findings do not present any significant evidence for associations between variants in IL-22 signaling pathway genes and CRC. Complementary studies with greater sample sizes may be necessary to fully elucidate the nature of these associations.

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关键词

Colorectal cancer,Interleukin-22 gene,Interleukin-22 receptor A1 gene,PCR-RFLP,Single nucleotide polymorphism

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