Racial differences in dysregulation of the renin-angiotensin-aldosterone system in patients with prurigo nodularis

Nishadh Sutaria,Melika Marani,Justin Choi,Youkyung Sophie Roh,Varsha Parthasarathy,Junwen Deng,Zachary A Bordeaux,Matthew T Taylor,Kevin K Lee,Thomas Pritchard,Ali Alajmi,Waleed Adawi,Yevgeniy R Semenov,Martin P Alphonse,Shawn G Kwatra

Journal of Dermatological Science（2022）

引用 7|浏览11

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摘要

•Prurigo nodularis (PN) is strongly associated with various renal comorbidities.•Association with renal comorbidities is stronger in black patients.•There is systemic and cutaneous dysregulation of the renin-angiotensin-aldosterone system (RAAS) in PN.•Dysregulation of the RAAS is stronger in black patients with prurigo nodularis.

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关键词

Prurigo nodularis,Comorbidities,Renin-angiotensin-aldosterone system,Racial,Itch,Pruritus

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