Health-related quality of life in homozygous familial hypercholesterolemia: A systematic review and meta-analysis

Latifah Alothman,Alexandre M Bélanger,Isabelle Ruel,Liam R Brunham,Lindsay Hales,Jacques Genest,Leo E Akioyamen

Journal of Clinical Lipidology（2022）

引用 6|浏览6

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摘要

•HoFH is associated with a significant treatment burden for affected patients.•HoFH patients experience notable impairments in nearly all domains of HRQoL.•HoFH adversely impacts self-perceptions education, and employment opportunities.•HoFH patients received little psychological support.

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关键词

Hypercholesterolemia,homozygous familial hypercholesterolemia,Depression,Quality of life,Orphan diseases

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