Whole brain mapping of glutamate distribution in adult and old primates at 11.7T

•Glutamate, a critical amino acid for the brain, can be detected by gluCEST imaging.•Whole brain gluCEST maps were recorded at high field (11.7T) MRI in a primate.•Regional differences of gluCEST contrast strongly reflect glutamate pathways.•gluCEST imaging highlights regional age-related alterations.•gluCEST imaging highlights age-related alterations in large-scale networks.