Trends, patterns, and maternal characteristics of opioid prescribing during pregnancy in a large population-based cohort study

•No study has linked PDMP and birth certificate data.•This can provide population-based data on prenatal opioid prescribing patterns.•Prenatal opioid prescriptions decreased over time, but prevalence was still 12%.•Opioid use was associated with lower education and income, obesity, and smoking.