Analytical validation of automated multiplex chromogenic immunohistochemistry for diagnostic and predictive purpose in non-small cell lung cancer

Marius Ilié,Mélanie Beaulande,Elodie Long-Mira,Christophe Bontoux,Katia Zahaf,Salomé Lalvée,Marame Hamila,Jonathan Benzaquen,Charlotte Cohen,Jean-Philippe Berthet,Charles-Hugo Marquette,Sandra Lassalle,Véronique Hofman,Paul Hofman

Lung Cancer（2022）

引用 11|浏览6

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摘要

•mIHC maximizes tissue preservation for further molecular analyses.•The validation of mIHC for routine clinical laboratory processes is mandatory.•We validated two mIHC assays to characterize NSCLC histotypes predictive biomarkers.•Standardized protocols are available on a widely available IHC autostainer.

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关键词

FFPE,LADC,LSCC,mIHC,NSCLC,RUO,TPS

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