Endocarditis Caused by Nontypeable Streptococcus pneumoniae

CLINICAL INFECTIOUS DISEASES(2022)

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摘要
The Streptococcus pneumoniae capsule is regarded as indispensable in bacteremia. We report an infant with a ventricular septal defect and infective endocarditis caused by nontypeable S. pneumoniae. In-depth investigation confirmed a deficient capsule yet favored pneumococcal fitness for causing infective endocarditis, rather than a host immune disorder, as the cause of infective endocarditis in this case.
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关键词
infective endocarditis, Streptococcus pneumoniae, bacterial polysaccharide capsule, pathogenesis
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