Joint risk prediction for hazardous use of alcohol, cannabis, and tobacco among adolescents: A preliminary study using statistical and machine learning

•A risk prediction model for hazardous substance use among adolescents is proposed.•The model predicts risk of hazardous use of alcohol, cannabis, and tobacco jointly.•It uses statistical and machine learning methods for modeling of multiple outcomes.•It may help identify adolescent users at elevated risk of hazardous substance use.