High-resolution inhibition profiling and ligand fishing for screening of nucleoside hydrolase ligands in Moringa oleifera Lamarck

Rachel A de Faria,Pamella C O Oliveira, Mariana D P de Carvalho,Bruno S Peixoto,Vanessa G P Severino,Luzineide W Tinoco,Silvana V Rodrigues,Marcela C de Moraes

Journal of Pharmaceutical and Biomedical Analysis（2022）

引用 2|浏览7

暂无评分

摘要

•A straightforward LdNH activity assay was developed.•Moringa oleifera leaves and flowers extracts as natural products library.•Ten ligands identified by high-resolution inhibition profiling and ligand fishing.•Seven ligands characterized by LC-HRMS.

查看译文

关键词

Nucleoside hydrolase,Moringa,Screening assays,High-resolution inhibition profiling,Ligand fishing,Leishmaniasis

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要