Higher ACE2 expression in the brains of individuals with Alzheimer's disease.

Louise Reveret,Manon Leclerc,Vincent Emond,Andréanne Loiselle, Philippe Bourassa,Cyntia Tremblay,David A Bennett,Sébastien Hébert,Frederic Calon

Alzheimer's & dementia : the journal of the Alzheimer's Association（2021）

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摘要

Our data suggest that cognitive impairment is associated with higher levels of ACE2 in the brain, which might contribute the higher risk of CNS SARS-CoV-2 infection in cognitively impaired individuals and AD patients.

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