Expression quantitative trait loci (eQTL) analysis in a diverse Alzheimer disease cohort reveals ancestry-specific regulatory architectures.

Anthony J Griswold,Olivia K Gardner,Briseida E Feliciano-Astacio,Derek Van Booven,Kara L Hamilton-Nelson,Patrice L Whitehead,Larry D Adams,Takiyah D Starks,Heriberto Acosta,Michael L Cuccaro,Jeffery M Vance,Goldie S Byrd,Jonathan L Haines,William S Bush,Gary W Beecham,Margaret A Pericak-Vance

Alzheimer's & dementia : the journal of the Alzheimer's Association（2021）

引用 1|浏览3

暂无评分

摘要

AA, NHW, and PR individuals have overlapping regulatory architecture that likely reflects the admixture in AA (20% European, 80% African) and PR (∼60% European, 20% African, and 20% Amerindian). These results underscore the importance of continuing to include diverse populations in AD genomics and functional studies to identify unique and shared architecture of AD.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要