Characterization of regulatory roles of genetic signals curated from more than 200 GWA studies in the Alzheimer's Disease Variant Portal (ADVP).

Yuk Yee Leung,Pavel P Kuksa,Yi-Fan Chou,Chia-Lun Liu,Wei Fu,Liming Qu,Yi Zhao,Zivadin Katanic,Amanda B Kuzma,Pei-Chuan Ho,Kai-Teh Tzeng,Otto Valladares,Shin-Yi Chou,Adam C Naj,Gerard D Schellenberg,Li-San Wang

Alzheimer's & dementia : the journal of the Alzheimer's Association（2021）

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摘要

Conducted analysis of genetic associations across >200 GWASs in ADVP and identified known AD culprit genes, relevant tissue/cell type categories, and regulatory mechanisms.

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