The effects of cancer therapies on physical fitness before oesophagogastric cancer surgery: a prospective, blinded, multi-centre, observational, cohort study [version 1; peer review: 2 approved].

Malcolm A West, Zachos Anastasiou,Gareth Ambler,Lisa Loughney,Michael G Mythen,Thomas Owen,Gerard Danjoux,Denny Z H Levett,Peter M A Calverley,Jamie J Kelly,Sandy Jack,Michael P W Grocott

NIHR open research（2021）

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摘要

Chemo/chemoradiotherapy prior to oesophagogastric cancer surgery reduced physical fitness. Lower baseline fitness was associated with reduced overall survival at one-year. Careful consideration of fitness prior to chemo/chemoradiotherapy and surgery is urgently needed.

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关键词

O2 diffusion during exercise,Pre-operative evaluation: American College of Cardiology Guidelines

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