A clinical and in-silico study of MicroRNA-21 and growth differentiation factor-15 expression in pre-diabetes, type 2 diabetes and diabetic nephropathy.

Riddhi G Agarwal,Manoj Khokhar,Purvi Purohit,Anupama Modi,Nitin K Bajpai,Gopal K Bohra,Mahendra K Garg,Praveen Sharma

Minerva endocrinology（2022）

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摘要

We suggest the potential of serum GDF15 and circulating-hsa-miR-21 to serve as clinically important biomarkers and therapeutic targets for controlling advancement of diabetes to DN.

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KEY woRDs, Biomarkers, Diabetic nephropathies, MicroRNAs, Type 2 diabetes mellitus, Transforming growth factor beta

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