Imidazole-induced manganese oxide nanocrystals on carbon nanofiber hybridized with gold nanoparticles as bifunctional biomimetic enzyme in live-cell assays

A bifunctional biomimetic enzyme towards H2O2 and O2− is designed and fabricated based on an aromatic molecule imidazole, which induces manganese oxide on acidified carbon nanofiber that is further hybridized with Au nanoparticles to form a nanocomposite. The nanocomposite-based electrochemical chips demonstrate their real-time and quantitative detection of H2O2 and O2− in live-cell assay.