Rationale and Design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a Randomized Controlled Trial Evaluating Tranexamic Acid and a Strategy to Minimize Hypotension in Noncardiac Surgery Population Health Research Institute , Royal Adelaide Hospital , University of Melbourne , Novosibirsk State University , Sessler Daniel , Chan Matthew T. V. , Martínez Zapata Maria J. , Wang C. Y. , Xavier Denis , Vita-Salute San Raffaele University , Efremov Sergey , Kleinlugtenbelt Ydo V. , Szczeklik Wojciech , Schmartz Denis , Western University , School of Health Sciences , Wittmann Maria , Meyhoff Christian S. , Amir Mohammed , Universidad de Los Andes , Patel Ameen , Universite de Montreal , Ruetzler Kurtz , Parlow Joel L. , Tandon Vikas , Fleischmann Edith , Hospital de Clínicas de Porto Alegre , Jayaram Raja , Rao Mangala , VanHelder Tomas , Wu William K. K. , Cheong Chao Chia , Ayad Sabry , Abubakirov Marat , Kirov Mikhail , Bhatt Keyur , de Nadal Miriam , M. Vladimirskiy Moscow Regional Clinical and Research Institute , Iglesisas Pilar Paniagua , Aguado Hector J. , McMaster University , Roshanov Pavel , Stillo David , Copland Ingrid , Vincent Jessica , Balasubramanian Kumar , Biccard Bruce , Medical University Graz , Srinathan Sadeesh , Petit Shirley , Richards Toby , Gross Peter L. , Alfonsi Pascal , Guyatt Gordon Trials（2022）
关键词
Noncardiac surgery, Tranexamic acid, Perioperative bleeding, Perioperative hypotension, Cardiovascular complications, Randomized controlled trial
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