Macrophage migration inhibitory factor regulates specific innate immune sensor responses in gingival epithelial cells.

Nutthapong Kantrong,Ana M Chang,Shatha Bamashmous,Adeline M Hajjar,Richard J Bucala,Richard P Darveau

Journal of periodontology（2022）

引用 3|浏览15

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摘要

MIF regulates the expression of TLR4, IL-1Rs, and IL-8/CXCL8, components that are all involved in maintaining oral health. Our data demonstrate that MIF is a significant contributor to the maintenance of healthy oral homeostasis.

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关键词

interleukin-1 receptors,junctional epithelium,macrophage migration inhibitory factor,neutrophils,periodontium,toll-like receptor 4

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