Human Dermcidin Protects Mice Against Hepatic Ischemia-Reperfusion-Induced Local and Remote Inflammatory Injury.

Xiaoling Qiang, Jianhua Li,Shu Zhu,Mingzhu He,Weiqiang Chen,Yousef Al-Abed,Max Brenner,Kevin J Tracey,Ping Wang,Haichao Wang

Frontiers in immunology（2021）

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摘要

The present study suggests that human DCD and its analog may be developed as novel therapeutics to attenuate hepatic I/R-induced inflammatory injury possibly by impairing EGFR signaling.

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关键词

EGFR,chemokine,dermcidin,inflammation,neutrophil,tissue injury

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