Hypophagia induced by salmon calcitonin, but not by amylin, is partially driven by malaise and is mediated by CGRP neurons

Molecular Metabolism(2022)

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摘要
•CGRP neurons mediate the effect of the amylin agonist salmon calcitonin (sCT) on food intake.•Amylin's hypophagic effect does not require CGRP neurons.•sCT-induced anorexia but not amylin is associated with malaise.
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关键词
Calcitonin gene-related peptides neurons,Hindbrain,Lateral parabrachial nucleus,Aversion,Emesis,Suncus murinus
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