Spinal Cord Stimulation Attenuates Neural Remodeling, Inflammation, and Fibrosis After Myocardial Infarction

Yuxian He,Zewei Sun,Jiajia Jiang,Xiang Yin,Jie Han,Yuanyuan Zhang,Liangrong Zheng

Neuromodulation: Technology at the Neural Interface（2023）

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摘要

SCS improved abnormal autonomic activity after MI, leading to reduced inflammation, reactivation of STAT3, and inhibition of Erk. Additionally, SCS attenuated myocardial fibrosis. Our results warrant future studies of biological mechanisms of the therapeutic effects of SCS after MI.

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关键词

Autonomic remodeling,inflammation,myocardial fibrosis,myocardial infarction,spinal cord stimulation

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