Evaluating the alginate oligosaccharide (OligoG) as a therapy for Burkholderia cepacia complex cystic fibrosis lung infection

Rianald Fischer,Carsten Schwarz,Rebecca Weiser,Eshwar Mahenthiralingam,Knut Smerud,Nils Meland,Hugo Flaten,Philip D Rye

Journal of Cystic Fibrosis（2022）

引用 3|浏览7

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摘要

•Alginate oligosaccharide OligoG shows favourable safety profile for inhalation in CF.•QoL summary scores showed minor relative improvement with OligoG treatment.•OligoG may have some effect in reducing Burkholderia spp. infection.•Rheology analysis showed a beneficial effect of OligoG on sputum viscosity.

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关键词

Cystic fibrosis,OligoG,Alginate oligosaccharide,Burkholderia cepacia complex (Bcc) bacteria,FEV1

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