Advances in the Development of Trifluoromethoxylation Reagents

Qian Wang,Xin Zhang,Alexander E. Sorochinsky,Greg Butler,Jianlin Han,Vadim A. Soloshonok

SYMMETRY-BASEL（2021）

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摘要

This review provides a short summary of the traditional methods for synthesis of CF3-O-containing compounds, followed by a critical overview of known trifluoromethoxylating reagents, focusing on their preparation, synthetic generality and limitations.

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关键词

pharmaceutical drugs, agrochemicals, trifluoromethoxylation, trifluoromethylation, fluorination, reagents

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