A Comparative Analysis of Ascorbic Acid-induced Cytotoxicity and Differentiation between SHED and DPSC.

Intan Zarina Zainol Abidin,Thanaletchumi Manogaran,Rohaya Megat Abdul Wahab, Farinawati Yazid,Shahrul Hisham Zainal Ariffin

Current stem cell research & therapy（2022）

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摘要

SHEDs survive at higher concentrations of ascorbic acid as compared to DPSC. The cytotoxic effect was only exhibited at ≥250 μg/mL ascorbic acid. In addition, SHED exhibited better ALP and mineralization activities, but lower osteoblast marker expression than DPSC in response to ascorbic acid as the sole inducer.

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关键词

Comparative,DPSC,SHED,ascorbic acid,cytotoxicity,osteoblast differentiation

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