Infective endocarditis nightmare: a bold solution for a devastating scenario.

Infective endocarditis still has significant morbimortality, despite diagnostic and therapeutic improvements. We describe a case of a 67-year-old man with recurrent prosthetic aortic valve infective endocarditis complicated by massive local tissue damage, making valve replacement unfeasible. Although rarely performed in this setting, heart transplantation was a needed salvage strategy, highlighting the need to make bold decisions for complex clinical scenarios.