SELENOT Deficiency in the Mouse Brain Impacts Catecholaminergic Neuron Density: An Immunohistochemical, in situ Hybridization and 3D Light-Sheet Imaging Study.

David Godefroy,Loubna Boukhzar,Ben Yamine Mallouki,Emmanuelle Carpentier,Christophe Dubessy,Fatiha Chigr,Yves Tillet,Youssef Anouar

Neuroendocrinology（2023）

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摘要

These results showed that SELENOT is diffusely expressed in the mouse brain and that its deficiency impacts CA neuron distribution in different brain areas including Hyp-A12-A14-A15, in both male and female mice.

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关键词

Catecholaminergic neuron,Light-sheet imaging,Selenoprotein T,Tyrosine hydroxylase,iDISCO+

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