Walking the LINEs hidden in the dark matter of the genome

NATURE GENETICS（2022）

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摘要

The function of transposable elements present in mammalian genomes remains an enigma. In this issue, Bodega, Abrignani and colleagues show that LINE1-containing transcripts are key regulators of T cell effector function and exhaustion.

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关键词

Gene regulation,Genetics,Immunology,Biomedicine,general,Human Genetics,Cancer Research,Agriculture,Gene Function,Animal Genetics and Genomics

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