Primary squamous cell carcinoma of the kidney parenchyma with ascending colon invasion: A case report and literature review

•Primary SCC arising in the urinary tract is an uncommon neoplasm, and the urinary bladder and male urethra are more frequent sites of SCC than the kidney.•SCC of the urinary tract was considered to arise from a process of metaplasia, particularly keratinizing squamous metaplasia of the urothelium.•Although the prognosis of primary kidney SCC is not different between urothelial carcinoma and SCC of the same stage, patients with SCC tend to be diagnosed at a more advanced stage.•There are no standard guidelines for management; radical nephrectomy tends to be the primary treatment, even in patients with metastatic disease.•In patients with receptor-positive primary SCC of the kidney, anti-EGFR therapy can be an another treatment option.