Prevalence, toxin-typing and antimicrobial susceptibility of Clostridium perfringens in sheep with different feeding modes from Gansu and Qinghai provinces, China

•C. perfringens was isolated from 14.7% of sheep and 45% of Tibetan sheep.•Detection rate of beta-2 coding gene cpb2 was higher in the isolates from sheep.•11 antimicrobial-resistance genes were detected in the sequenced isolates.•C. perfringens isolates from same source shared closer genetic relationship.