A simultaneous multi-slice T-2 mapping framework based on overlapping-echo detachment planar imaging and deep learning reconstruction
MAGNETIC RESONANCE IN MEDICINE(2022)
摘要
Purpose Quantitative MRI (qMRI) is of great importance to clinical medicine and scientific research. However, most qMRI techniques are time-consuming and sensitive to motion, especially when a large 3D volume is imaged. To accelerate the acquisition, a framework is proposed to realize reliable simultaneous multi-slice T-2 mapping. Methods The simultaneous multi-slice T-2 mapping framework is based on overlapping-echo detachment (OLED) planar imaging (dubbed SMS-OLED). Multi-slice overlapping-echo signals were generated by multiple excitation pulses together with echo-shifting gradients. The signals were excited and acquired with a single-channel coil. U-Net was used to reconstruct T-2 maps from the acquired overlapping-echo image. Results Single-shot double-slice and two-shot triple-slice SMS-OLED scan schemes were designed according to the framework for evaluation. Simulations, water phantom, and in vivo rat brain experiments were carried out. Overlapping-echo signals were acquired, and T-2 maps were reconstructed and compared with references. The results demonstrate the superior performance of our method. Conclusion Two slices of T-2 maps can be obtained in a single shot within hundreds of milliseconds. Higher quality multi-slice T-2 maps can be obtained via multiple shots. SMS-OLED provides a lower specific absorption rate scheme compared with conventional SMS methods with a coil with only a single receiver channel. The new method is of potential in dynamic qMRI and functional qMRI where temporal resolution is vital.
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关键词
deep learning, MRI, overlapping echoes, simultaneous multi-slice, T-2 mapping
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