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Point Mutation I634A in the Glucocorticoid Receptor Causes Embryonic Lethality by Reduced Ligand Binding

Steven Timmermans,Nicolette J. D. Verhoog,Kelly Van Looveren,Sylviane Dewaele,Tino Hochepied,Melanie Eggermont,Barbara Gilbert,Anne Boerema-de Munck,Tineke Vanderhaeghen,Joke Vanden Berghe,Natalia Garcia Gonzalez,Jolien Vandewalle,Yehudi Bloch,Mathias Provost,Savvas N. Savvides,Karolien De Bosscher,Wim Declercq,Robbert J. Rottier,Ann Louw,Claude Libert

Journal of Biological Chemistry（2022）

Cited 9|Views25
Key words
glucocorticoid receptor,mutational study,A465T,I634A,dimerization,ligand binding
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