LITE SABR M1: Planning design and dosimetric endpoints for a phase I trial of lattice SBRT

James A Kavanaugh,Matthew B Spraker,Sai Duriseti,Franco Basarabescu,Alex Price,Murty Goddu,Nels Knutson,Michael Prusator,Clifford Robinson,Thomas Mazur

Radiotherapy and Oncology（2022）

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摘要

•Refined treatment planning techniques improve Lattice SBRT plan quality.•Patient treatment times for Lattice SBRT are scheduled in standard time slots.•All treatment plan quality objectives are achievable.•Existing plan evaluation metrics are insensitive to dose gradient variations.•Updated planning metrics quantify deviations of dose gradients within targets.

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关键词

Lattice SBRT,Spatially fractionated radiation therapy,Phase I trial,Treatment planning metrics

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