Predicting personalised absolute treatment effects in individual participant data meta-analysis: An introduction to splines

Michail Belias,Maroeska M Rovers,Jeroen Hoogland,Johannes B Reitsma,Thomas P A Debray,Joanna IntHout

RESEARCH SYNTHESIS METHODS（2022）

引用 4|浏览9

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摘要

We provide guidance on the use of splines in IPD-MA, to capture heterogeneous treatment effects in presence of non-linear associations, thereby facilitating estimation of absolute treatment effects to enhance personalized healthcare.

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