Dietary choline is inversely associated with depressive symptoms: A cross-sectional study of the National Health and Nutrition Examination Survey (NHANES) 2011 to 2018

•No epidemiological studies to explore the association between dietary choline and depressive symptoms  in US general population.•No studies to explore the dose-response relationship between dietary choline and depressive symptoms.•Our results suggested that the intake of dietary choline was negatively associated with the risk of depressive symptoms.•An L-shaped dose-response relationships were found between dietary choline and depressive symptoms in U.S. adults.