Model-Based Selection for Proton Therapy in Breast Cancer: Development of the National Indication Protocol for Proton Therapy and First Clinical Experiences

L J Boersma,M G A Sattler,J H Maduro, N Bijker, M Essers, C M J van Gestel, Y L B Klaver,A L Petoukhova,M F Rodrigues, N S Russell,A van der Schaaf, K Verhoeven, M van Vulpen,E Schuit,J A Langendijk

Clinical Oncology（2022）

引用 14|浏览12

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摘要

•Selection protocol was determined for proton therapy for breast cancer patients.•Prediction of lifetime risk of acute coronary events based on mean heart dose.•About 3–4% of breast cancer patients are expected to benefit from proton therapy.

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关键词

Acute coronary events,breast cancer,cardiac toxicity,model-based selection,prognostic models,proton therapy

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