Acquired mild cognitive impairment in adults with Down syndrome: Age-related prevalence derived from single point assessment data normed by degree of intellectual disability.

Chris Oliver,Dawn Adams,Anthony J Holland,Stephanie S G Brown,Sarah Ball,Karen Dodd, Janet Carr

International journal of geriatric psychiatry（2021）

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摘要

Psychometric data indicate single point assessment of AMCI is possible for the majority of adults with DS. Two peaks for age-related prevalence of AMCI suggest the risk for onset of AD conferred by trisomy of chromosome 21 is moderated by another factor, possibly ApoE status.

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关键词

Alzheimer's disease,Down syndrome,ageing,dementia,intellectual disability,mild cognitive impairment,neuropsychological assessment

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