Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma

Matt Lechner,Yoko Takahashi,Mario Turri-Zanoni,Jacklyn Liu,Nicholas Counsell,Mario Hermsen,Raman Preet Kaur,Tianna Zhao,Murugappan Ramanathan,Volker H Schartinger,Oscar Emanuel,Sam Helman,Jordan Varghese,Jozsef Dudas,Herbert Riechelmann,Susanne Sprung,Johannes Haybaeck,David Howard,Nils Wolfgang Engel,Sarah Stewart,Laura Brooks,Jessica C Pickles,Thomas S Jacques,Tim R Fenton,Luke Williams,Francis M Vaz,Paul O'Flynn,Paul Stimpson,Simon Wang,S Alam Hannan,Samit Unadkat,Jonathan Hughes,Raghav Dwivedi,Cillian T Forde,Premjit Randhawa,Simon Gane,Jonathan Joseph,Peter J Andrews,Gary Royle,Alessandro Franchi,Roberta Maragliano,Simonetta Battocchio,Helen Bewicke-Copley,Christodoulos Pipinikas,Amy Webster,Chrissie Thirlwell,Debbie Ho,Andrew Teschendorff,Tianyu Zhu,Christopher D Steele,Nischalan Pillay,Bart Vanhaesebroeck,Ahmed Mohyeldin,Juan Fernandez-Miranda,Ki Wan Park,Quynh-Thu Le,Robert B West,Rami Saade,R Peter Manes,Sacit Bulent Omay,Eugenia M Vining,Benjamin L Judson,Wendell G Yarbrough,Maddalena Sansovini,Nicolini Silvia,Ilaria Grassi,Alberto Bongiovanni,David Capper,Ulrich Schüller,Selvam Thavaraj,Ann Sandison,Pavol Surda,Claire Hopkins,Marco Ferrari,Davide Mattavelli,Vittorio Rampinelli,Fabio Facchetti,Piero Nicolai,Paolo Bossi,Oswaldo A Henriquez,Kelly Magliocca,C Arturo Solares,Sarah K Wise,Jose L Llorente,Zara M Patel,Jayakar V Nayak,Peter H Hwang, Peter D Lacy,Robbie Woods, James P O'Neill,Amrita Jay,Dawn Carnell,Martin D Forster,Masaru Ishii,Nyall R London,Diana M Bell,Gary L Gallia,Paolo Castelnuovo,Stefano Severi,Valerie J Lund,Ehab Y Hanna

European Journal of Cancer（2022）

引用 19|浏览48

暂无评分

摘要

•Dural infiltration is prognostic and integrated into the Kadish-INSICA staging system (International Network for Sinonasal Cancer and Skull Base Tumours (www.insica.org).•Adjuvant radiotherapy is beneficial across all stage groups, including early stage.•Prophylactic neck irradiation prevents neck nodal recurrence.•82.4% express Somatostatin Receptor 2 (SSTR2) protein which can be used for SSTR2-targeted imaging.•SSTR2-targeted peptide receptor radionuclide therapy is useful in metastatic disease.

查看译文

关键词

Esthesioneuroblastoma,Olfactory,Prognosis,Radiotherapy,Adjuvant,SSTR2 protein,Human,Receptors,Somatostatin,Diagnostic imaging

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要