Genome-wide analysis identified abundant genetic modulators of contributions of the apolipoprotein E alleles to Alzheimer's disease risk.
Alzheimer's & dementia : the journal of the Alzheimer's Association（2022）
摘要
These findings suggest involvement of local and inter-chromosomal modulators of the effects of the APOE alleles on the AD risk.
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关键词
APOE,Cox regression,age at onset,aging,dementia,genetic modulators,genetic polymorphisms,genome-wide association studies,neurodegenerative diseases,sex-specific associations
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