Prevalence and antimicrobial susceptibility level of typhoid fever in Ethiopia: A systematic review and meta-analysis

•The diagnosis of typhoid fever was under or overestimated depending on the diagnostic modality.•Widal test is none reliable diagnosis method of typhoid fever causing high diagnosis uncertainty.•Salmonella S. Typhi was resistant for most nationally recommended antibiotics in Ethiopia.•Continued monitoring and surveillance is needed to inform the rising resistance of S. Typhi.•Evidence-based decision-making on the diagnosis and resistance of typhoid fever is crucial.