Is there a ceiling lamotrigine serum level in epileptic children in remission?

Rim Charfi,Emna Gaies,Mouna Ben Sassi,Hanene El Jebari, Rania Kammoun, Israa Dahmene,Nadia Jebabli,Issam Salouage,Riadh Daghfous,Sameh Trabelsi

Therapies（2022）

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摘要

Children in remission had a LMT trough serum levels under 11μg/mL and a daily dose of 3.36mg/kg/day or less. These results suggest that this LMT serum level and daily dose might be associated with a ceiling effect in epileptic children.

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关键词

Therapeutic drug monitoring,Lamotrigine,Children,Epilepsy

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