Iterative Learning Pressure and Flow Control of a Bioreactor for Tissue Engineered Heart Valves

During the in vitro maturation process of tissue engineered heart valves in a bioreactor, the pressures ahead of and behind the heart valve as well as the transvalvular flow rate strongly influence the tissue development. In this paper, a norm-optimal iterative learning control scheme for the control of these three process input variables within a new bioreactor setup is introduced and evaluated u...