High-content screening of Alzheimer's disease genetic risk factors based on synaptic density analysis.

Audrey Coulon,Tiago Mendes,Devrim Kilinc,Julie Dumont,Julien Chapuis,Jean-Charles Lambert

Alzheimer's & dementia : the journal of the Alzheimer's Association（2021）

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摘要

We have developed a high-content screening approach which allows us to define the genetic risk factors that are involved in the pathophysiological synaptic dysregulation observed in the early stages of AD.

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