Alzheimer’s disease susceptibility locus in CD2AP is associated with increased cerebrospinal fluid tau levels in mild cognitive impairment

Yan-Yan Xue,Yi-He Chen,Rong-Rong Lin,Hui-Fen Huang,Zhi-Ying Wu,Qing-Qing Tao

Neuroscience Letters（2022）

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摘要

•There was no association between CSF Aβ1–42 level and CD2AP rs9296559 SNP in CN, MCI or AD.•CC + TC genotype of rs9296559 was associated with increased CSF tau levels in MCI.•CC + TC genotype of rs9296559 did not alter CSF tau levels in CN or AD.

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关键词

Alzheimer’s disease,CD2AP,Rs9296559,Tau,Cerebrospinal fluid tau

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