Analysis of serum HE4 levels in various histologic subtypes of epithelial ovarian cancer and other malignant tumors.

Alexandra Blackman, Jessica Mitchell,Rachael Rowswell-Turner,Rakesh Singh,Kyu Kwang Kim,Elizabeth Eklund,Steven Skates,Robert C Bast,Geralyn Messerlian,M Craig Miller,Richard G Moore

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine（2021）

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摘要

Serum HE4 levels are most often elevated in women with high grade serous and endometrioid EOCs, and though serum elevations are seen more often with advanced stage disease, HE4 is also often elevated in early stage disease and lower grade tumors.

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Serum HE4,biomarker,ovarian cancer

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